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Floris from Blossom

I write about the science and implementation of psychedelics as medicines. Join to learn alongside me and make the future happen sooner!

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The Bloom 187 - Busy November

The Bloom #187 Free Edition crossdiagnostic effects In November, I added twice as many studies to the database as in October. We have a long-term follow-up on MDMA for depression (showing promising results), possibly the most rigorous microdosing study to date (with large - but placebo-driven - effects), and a simulation of psychedelics for disorders of consciousness. See all new studies in the full November Recap. Floris - Founder of Blossom ps Behind the scenes, I'm hard at work on building...

The Bloom #186 Free Edition micro effects Last month was a decidedly slow month for psychedelic research. I only added seven studies to the database, and 'only' came across 140 studies (versus nearly 200 in the months before). Still, there were interesting investigations of microdosing (null result), emotional reactivity (btter in psychonauts), a third generation psychedelic (GM-2505), set and setting (in cancer-related depression), brain plasticity (context dependent), endocannabinoid levels...

The Bloom #185 Free Edition Lysene, not Lykos Next to research in clinical populations, the latest psychedelic research papers take a closer look at specific mechanisms and comparisons of similar compounds. We get a view into the differences between methamphetamine and MDMA, look at MDMA versus MDA (and their prodrugs), and look at fMRI data from a pharmuasca study (DMT + harmine). I cover lots more in the research recap for September. Floris - Founder of Blossom ps My friends at the...

The Bloom #184 Free Edition being the White Rabbit Normally, I would email you once every two weeks. But it's been nearly six weeks since the last Bloom. I'm fully caught up with the latest research (also see the recap for August), but because of family circumstances, the next edition might come in a bit later too. See some of the most interesting studies below, and the full updates on our papers page and link overview (for paid subscribers only). Floris - Founder of Blossom ps there are some...

The Bloom #183 Free Edition research abundance The summer is a time to take it a bit slower and let new ideas surface. Psychedelic researchers clearly didn't get that memo. Last month, 181 new papers were published and 18 (just like in June) new articles have been added to the database (full recap here). We take a look at control groups in psychedelic trials, MDMA for depression, ibogaine EEG data, and much more below. Floris - Founder of Blossom Latest Psychedelic Research 1 Control Group...

The Bloom #182 Free Edition Europe awakens Between May and June, the number of research articles we've added to the database shot up by 80%. Ok, that is going from 10 to 18, but still, a lot of valuable research is hot off the press. You can read the full recap of June's research on Blossom. This month, more research has been published on the mystical experience, OCD, and psilocybin-assisted therapy for bipolar II. Looking forwards, many conferences are happening all around Europe. Here are a...

The Bloom #180 Free Edition integrate this Since the last newsletter, psychedelic research has made a 180-degree turn. Where before the research was a bit slow, the end of June proved to be fertile ground for the study of psychedelics. Instead of the three most interesting articles, see six featured below. In total, 18 new publications were added to the database in the past few weeks. We cover the first PET-MRI study of LSD, the first study of vaporised DMT, a long-term follow-up of...

The Bloom #180 Free Edition the science is my passion It is with great sadness and profound gratitude that I want to acknowledge the passing of psychedelic pioneer Amanda Fielding on May 22nd. As the driving force behind the psychedelic research renaissance, her visionary work has left an indelible mark on the field, and she will be dearly missed. See her obituary in The Economist here. Last month's research was relatively slow, and I've recapped it here. Floris - Founder of Blossom ps...

The Bloom #179 Free Edition building the infrastructure Thank you to everyone who filled in the Global Psychedelic Survey! In total, the survey got nearly 9000 responses. I'm expecting some exciting results from the survey in the coming year(s). Psychedelic research has been relatively slow. One area that I'm particularly interested in, the health economics of psychedelics (put more bluntly: will insurance want to pay for them), was bolstered by a comparative analysis of ketamine versus ECT...

The Bloom #178 Free Edition geolocating the hivemind The biggest psychedelic survey is running again this year. Adults 21+ from across the globe have the opportunity to participate in the most comprehensive assessment of psychedelic use amongst adults to date. Share your experiences by completing the Global Psychedelic Survey 2025 (GPS 2025). The survey will be available around the globe in 18 different languages. Please take the survey before May 16th. Floris - Founder of Blossom ps This...