The Bloom #154 Free Edition ketacol

I'm excited to share some updates alongside the latest psychedelic research articles. We've just completed a significant update to our trials database, now featuring 900 psychedelic trials sourced from ClinicalTrials.gov, national databases, company announcements, and more.

Floris - Founder of Blossom

ps My friend Henry writes the twice-weekly Tricycle Day newsletter with much more news on psychedelics, I highly recommend checking it out.

1 Esketamine combined with a mindfulness-based intervention for individuals with alcohol problems​

This double-blind, pilot study (n=28) investigates esketamine combined with mindfulness-based intervention (MBI) for individuals with alcohol misuse problems. Esketamine enhanced psychological engagement in MBI and transiently decreased alcohol cravings, while also resulting in greater mystical experiences and dissociative states compared to placebo.

Also, see this study from last week, which found no lasting effects (in a small population) of psychedelics on alcohol use: Effects of a Single Dose of Ayahuasca in College Students With Harmful Alcohol Use: A Single-blind, Feasibility, Proof-of-Concept Trial​

2 The Role of Music in Psychedelic-Assisted Therapy: A Comparative Analysis of Neuroscientific Research, Indigenous Entheogenic Ritual, and Contemporary Care Models​

This review evaluates the role of music in psychedelic-assisted therapies (PAT) and indigenous entheogenic ceremonies. It examines neuroscientific, psychological, and anthropological research, highlighting the need for personalized music protocols and the integration of traditional practices into modern treatment models to enhance clinical outcomes.

3 Developing an Ethics and Policy Framework for Psychedelic Clinical Care: A Consensus Statement​

This consensus statement (n=27) identifies key ethics and policy issues for integrating psychedelic therapies into clinical practice. It reports 20 points of consensus across 5 ethical issues, with relevant actors responsible for implementation, and highlights areas needing further research and deliberation.

More new research

• ​Time-resolved coupling between connectome harmonics and subjective experience under the psychedelic DMT​
• ​Functional changes in sleep-related arousal after ketamine administration in individuals with treatment-resistant depression​

New on Blossom

1 Psychedelic Research Recap May​

Psychedelic research in May 2024 investigates awe in ketamine therapy, role of therapy in PAT, touch guidelines, and more.

2 Psychedelic Research Links 2024​

All the other papers that have come out this year that don't have a separate entry in the database.

Spotlight

No spotlight this week.

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